In the study “Efficacy of antiplaque mouthwashes: a five day clinical trial” we evaluated the efficacy of using Fluoride containing toothpaste followed by use of Chlorhexidine mouthwash. The results indicated that Fluoride toothpaste should not be used simultaneously with a Chlorhexidine mouthwash as both tend to cancel each other’s therapeutic effects, as has been evidenced in the dental literature previously. It is suggested that a minimum of 30 minutes gap should be given between using Fluoride toothpaste and Chlorhexidine mouthwash. On the contrary, it was found that Cetylpyridinium chloride mouthwash when used with Fluoride containing toothpaste offered maximum antiplaque effect.

The study was originally published in General Dentistry journal in 2011. Click the picture below to download full research paper.

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